Kim Rosenthal

Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.

Avi Ashkenazi, Leonard G. Presta, Scot A. Marsters et al. · Proceedings of the National Academy of Sciences · 1990 · 177 citations

Life Sciences, Infectious Diseases, Molecular Biology +15

A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells

Heather K. Kroh, Ramyavardhanee Chandrasekaran, Zhifen Zhang et al. · Journal of Biological Chemistry · 2017 · 67 citations · Full text

Life Sciences, Immunology, Microbiology +10

Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates

David E. Tabor, Vaheh Oganesyan, Ashley Keller et al. · The Journal of Infectious Diseases · 2018 · 66 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +13

Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach

Christine Tkaczyk, Srinath Kasturirangan, Andrea Minola et al. · Antimicrobial Agents and Chemotherapy · 2017 · 40 citations · Full text

Pharmacy, Immunology, Pharmacology +17

Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity <i>In Vitro</i> and Staphylococcus aureus Fitness in Infection Models

Christine Tkaczyk, Yuru Shi, Kim Rosenthal et al. · Antimicrobial Agents and Chemotherapy · 2018 · 26 citations · Full text

Pharmacy, Infectious Diseases, Pharmacology +17