Maria Small

Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: The OCEAN study

Richard Eastell, Shinichi Nagase, Michiyo Ohyama et al. · Journal of Bone and Mineral Research · 2011 · 126 citations

Effect of ONO-5334 on Bone Mineral Density and Biochemical Markers of Bone Turnover in Postmenopausal Osteoporosis: 2-Year Results From the OCEAN Study

Richard Eastell, Shinichi Nagase, Maria Small et al. · Journal of Bone and Mineral Research · 2013 · 75 citations

Effect of escalating doses of recombinant human granulocyte colony—stimulating factor (filgrastim) on circulating neutrophils in healthy subjects

Jan C.C. Borleffs, Mike A.R. Bosschaert, H M Vrehen et al. · Clinical Therapeutics · 1998 · 48 citations

Inflammation, Healthy Subjects, Granulocyte +5

The Effect of the Cathepsin K Inhibitor ONO-5334 on Trabecular and Cortical Bone in Postmenopausal Osteoporosis: The OCEAN Study

Klaus Engelke, Shinichi Nagase, Thomas Fuerst et al. · Journal of Bone and Mineral Research · 2013 · 43 citations · Full text

Pharmacodynamic Effects on Biochemical Markers of Bone Turnover and Pharmacokinetics of the Cathepsin K Inhibitor, ONO‐5334, in an Ascending Multiple‐Dose, Phase 1 Study

Shinichi Nagase, Michiyo Ohyama, Yoshitaka Hashimoto et al. · The Journal of Clinical Pharmacology · 2011 · 27 citations

Bone Disease, Molecular Pharmacology, Bone Health +14