Davide Bassani

SARS-CoV-2 3CL ^pro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376

Emmanuel Heilmann, Francesco Costacurta, Seyed Arad Moghadasi et al. · Science Translational Medicine · 2022 · 131 citations · Full text

Qualitative Estimation of Protein–Ligand Complex Stability through Thermal Titration Molecular Dynamics Simulations

Matteo Pavan, Silvia Menin, Davide Bassani et al. · Journal of Chemical Information and Modeling · 2022 · 73 citations · Full text

Engineering, Qualitative Estimation, Molecular Biology +18

Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332

Matteo Pavan, Giovanni Bolcato, Davide Bassani et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2021 · 70 citations · Full text

1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation

Camilla Pecoraro, Michele De Franco, Daniela Carbone et al. · European Journal of Medicinal Chemistry · 2023 · 43 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +8

Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma

Daniela Carbone, Michele De Franco, Camilla Pecoraro et al. · International Journal of Molecular Sciences · 2023 · 37 citations · Full text