Structure–Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5′-Nucleotidase (CD73) Inhibitors

Anna Junker, Christian Renn, Clemens Dobelmann, +12

Journal of Medicinal Chemistry

Structure-Based Design of 3-(4-Aryl-1<i>H</i>-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y₁₄ Receptor Antagonists

Anna Junker, R. Balasubramanian, Antonella Ciancetta, +9

Journal of Medicinal Chemistry

Molecular DockingMolecular PharmacologyMedicinal ChemistryComputational PipelineDrug Target +12

Synthesis of Thiophene-Based TAK-779 Analogues by C–H Arylation

Anna Junker, Junichiro Yamaguchi, Kenichiro Itami, +1

The Journal of Organic Chemistry

Chemical EngineeringEngineeringThiophene System 2Late-stage Diversification StrategyCatalytic Synthesis +8

Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases

Daniel Gedder Silva, Anna Junker, Shaiani Maria Gil de Melo, +8

ChemMedChem

Bioorganic ChemistryAntiparasitic AgentAnti‐infective AgentsHeterocyclic CompoundsChemical Biology +16

Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease

Bengisu Turgutalp, Prabesh Bhattarai, Tuğba Erçeti̇n, +12

Journal of Medicinal Chemistry

Automated Counting of Cancer Cells by Ensembling Deep Features

Qian Liu, Anna Junker, Kazuhiro Murakami, +1

Cells

Structure–Activity Relationship of 3-Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors

Mirko Scortichini, Riham M. Idris, Susanne Moschütz, +13

Journal of Medicinal Chemistry

Synthesis, binding affinity and structure–activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Anna Junker, Artur K. Kokornaczyk, Annelien J.M. Zweemer, +13

Organic & Biomolecular Chemistry

Combinatorial ChemistryDual Targeting Ccr2ImmunologyMolecular BiologyHeterocycle Chemistry +14

Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold

Simone Thum, Artur K. Kokornaczyk, Tomoaki Seki, +11

European Journal of Medicinal Chemistry

Combinatorial ChemistryChemokine ReceptorBiochemistry2-Benzazepine ScaffoldMedicine +8

A Novel Convolutional Regression Network for Cell Counting

Qian Liu, Anna Junker, Kazuhiro Murakami, +1

Data AugmentationConvolutional Neural NetworkMachine VisionMachine LearningImage Analysis +13