Donald S. Middleton

Tandem [4 + 2]/[3 + 2] Cycloadditions of Nitroalkenes. 9. Synthesis of (−)-Rosmarinecine

Scott E. Denmark, Atli Thorarensen, Donald S. Middleton · Journal of the American Chemical Society · 1996 · 74 citations

Diversity Oriented Synthesis, Natural Product Synthesis, Bioorganic Chemistry +14

Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays

Lyn H. Jones, Gill Allan, Oscar Barba et al. · Journal of Medicinal Chemistry · 2009 · 55 citations · Full text

Combinatorial Chemistry, Molecular Biology, Pharmacotherapy +16

Tandem Inter [4 + 2]/Intra [3 + 2] Cycloadditions. 17. The Spiro Mode. Efficient and Highly Selective Synthesis of Azapropellanes

Scott E. Denmark, Donald S. Middleton · The Journal of Organic Chemistry · 1998 · 51 citations

Engineering, Highly Selective Synthesis, Face Selectivity +12

Structure−Activity Relationships of 1-Alkyl-5-(3,4-dichlorophenyl)- 5-{2-[(3-substituted)-1-azetidinyl]ethyl}-2-piperidones. 1. Selective Antagonists of the Neurokinin-2 Receptor

A. Mackenzie, Allan P. Marchington, Donald S. Middleton et al. · Journal of Medicinal Chemistry · 2002 · 50 citations · Full text

Nk2 Receptor, Pharmacotherapy, Rabbit Pulmonary Artery +18

Synthesis of spiroethers using radical cyclisations

Donald S. Middleton, Nigel S. Simpkins, Michael J. Begley et al. · Tetrahedron · 1990 · 47 citations

Organic Chemistry, Synthetic Chemistry, Chemistry +1