Shashirekha Shetty

An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities

Erin B. Kaminsky, Vineith Kaul, Justin Paschall et al. · Genetics in Medicine · 2011 · 444 citations · Full text

Intellectual Impairment, Psychiatry, Genetic Disorder +6

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

Andrew R. Morton, Nergiz Doğan, Zachary Faber et al. · Cell · 2019 · 351 citations · Full text

Chromatin, Genetics, Genomic Mechanism +5

NEK2 Induces Drug Resistance Mainly through Activation of Efflux Drug Pumps and Is Associated with Poor Prognosis in Myeloma and Other Cancers

Wen Zhou, Ye Yang, Jiliang Xia et al. · Cancer Cell · 2013 · 296 citations · Full text

Medicine, Efflux Drug Pumps, Pharmacology +9

Transcription Factor NF-κB Differentially Regulates Death Receptor 5 Expression Involving Histone Deacetylase 1

Shashirekha Shetty, Bonnie A. Graham, Jennifer G. Brown et al. · Molecular and Cellular Biology · 2005 · 136 citations · Full text

Hdac Inhibitors, Apoptosis, Immunology +20

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines

Shashirekha Shetty, J. Brown Gladden, Elizabeth S. Henson et al. · APOPTOSIS · 2002 · 91 citations