Pablo Leitzman

Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice

Sreekanth C. Narayanapillai, Pablo Leitzman, Maeve O’Sullivan et al. · Chemical Research in Toxicology · 2014 · 41 citations · Full text

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice

Sreekanth C. Narayanapillai, Silvia Balbo, Pablo Leitzman et al. · Carcinogenesis · 2014 · 41 citations · Full text

Chemoprevention Strategy, Pathology, Pharmacotherapy +23

Kava Blocks 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone–Induced Lung Tumorigenesis in Association with Reducing <i>O6</i> -methylguanine DNA Adduct in A/J Mice

Pablo Leitzman, Sreekanth C. Narayanapillai, Silvia Balbo et al. · Cancer Prevention Research · 2014 · 35 citations · Full text

Dihydromethysticin (DHM) Blocks Tobacco Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Induced<i>O</i>⁶-Methylguanine in a Manner Independent of the Aryl Hydrocarbon Receptor (AhR) Pathway in C57BL/6 Female Mice

Sreekanth C. Narayanapillai, Shang-Hsuan Lin, Pablo Leitzman et al. · Chemical Research in Toxicology · 2016 · 20 citations · Full text

Pilot in Vivo Structure–Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced <i>O</i>⁶-Methylguanine and Lung Tumor in A/J Mice

Manohar Puppala, Sreekanth C. Narayanapillai, Pablo Leitzman et al. · Journal of Medicinal Chemistry · 2017 · 19 citations · Full text