Concepedia

Houguang Shi

HS

4

Publications

165

Citations

4

H-Index

2017

Active since

Affiliations

Roche (China)(Current)

Roche (Switzerland)

Houguang Shi is an author at Roche (China) specializing in biomolecular engineering, viral hepatitis, and drug discovery.

Top concepts

Publications per year

2017–2023

4

Publications

4

Discovery of Pyrido[2,3-<i>b</i>]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV

Yimin Hu, Houguang Shi, Mingwei Zhou et al. · Journal of Medicinal Chemistry · 2020 · 65 citations

Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors

Zongxing Qiu, Xianfeng Lin, Weixing Zhang et al. · Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection

Weixing Zhang, Lei Guo, Haixia Liu et al. · Journal of Medicinal Chemistry · 2023 · 29 citations · Full text

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A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles

Xianfeng Lin, Houguang Shi, Weixing Zhang et al. · Journal of Medicinal Chemistry · 2019 · 13 citations · Full text

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