Nontarget Screening of Per- and Polyfluoroalkyl Substances Binding to Human Liver Fatty Acid Binding Protein

Diwen Yang, Jiajun Han, David Ross Hall, +8

Environmental Science & Technology

Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results

Carlie A. LaLone, Daniel L. Villeneuve, Jon A. Doering, +7

Environmental Science & Technology

A Cross-species Quantitative Adverse Outcome Pathway for Activation of the Aryl Hydrocarbon Receptor Leading to Early Life Stage Mortality in Birds and Fishes

Jon A. Doering, Steve Wiseman, John P. Giesy, +1

Environmental Science & Technology

Combined Transcriptomic and Proteomic Approach to Identify Toxicity Pathways in Early Life Stages of Japanese Medaka (<i>Oryzias latipes</i>) Exposed to 1,2,5,6-Tetrabromocyclooctane (TBCO)

Jianxian Sun, Song Tang, Hui Peng, +6

Environmental Science & Technology

μG/l TbcoPathologyProteomic ApproachReproductive BiologyComparative Toxicology +21

Sensitivity of early life stages of white sturgeon, rainbow trout, and fathead minnow to copper

David Vardy, Johanna Oellers, Jon A. Doering, +3

Ecotoxicology

Rainbow TroutFishery ScienceWhite SturgeonFish ImmunologyEarly Life Stages +1

The Eco-Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals

Stefan Scholz, John W. Nichols, Beate I. Escher, +20

Environmental Toxicology and Chemistry

Integrative Computational Approaches to Inform Relative Bioaccumulation Potential of Per- and Polyfluoroalkyl Substances Across Species

Weixiao Cheng, Jon A. Doering, Carlie A. LaLone, +1

Toxicological Sciences

BioconcentrationHuman LfabpEngineeringMolecular DynamicsChemical Contaminant +26

Differences in Activation of Aryl Hydrocarbon Receptors of White Sturgeon Relative to Lake Sturgeon Are Predicted by Identities of Key Amino Acids in the Ligand Binding Domain

Jon A. Doering, Reza Farmahin, Steve Wiseman, +4

Environmental Science & Technology

EcotoxicityAryl Hydrocarbon ReceptorsComparative ToxicologyToxicological MechanismKey Amino Acids +15

High Conservation in Transcriptomic and Proteomic Response of White Sturgeon to Equipotent Concentrations of 2,3,7,8-TCDD, PCB 77, and Benzo[a]pyrene

Jon A. Doering, Song Tang, Hui Peng, +5

Environmental Science & Technology

GeneticsToxicological MechanismOxidative StressAdverse EffectsPcb 77 +18

Quantitative Response-Response Relationships Linking Aromatase Inhibition to Decreased Fecundity are Conserved Across Three Fishes with Asynchronous Oocyte Development

Jon A. Doering, Daniel L. Villeneuve, Shane Poole, +8

Environmental Science & Technology