Pravien Abeywickrema

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

Hua-Poo Su, Youwei Yan, G. Sridhar Prasad et al. · Journal of Virology · 2010 · 96 citations · Full text

The discovery of fused pyrrole carboxylic acids as novel, potent d-amino acid oxidase (DAO) inhibitors

Tim Sparey, Pravien Abeywickrema, Sarah Almond et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 82 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +7

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9

Whitney L. Petrilli, Gregory C. Adam, Roman S. Erdmann et al. · Cell chemical biology · 2019 · 80 citations · Full text

Biochemistry, Medicine, Natural Sciences +9

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

S.M. Soisson, Sangita B. Patel, Pravien Abeywickrema et al. · BMC Structural Biology · 2010 · 55 citations · Full text

Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors

Izzat T. Raheem, Abbas M. Walji, Daniel J. Klein et al. · Journal of Medicinal Chemistry · 2015 · 36 citations

Lead Compounds, Pharmacotherapy, Antiviral Drug +19