Toshihiro Hamajima

Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase

Nicholas D. Adams, Jerry L. Adams, Joelle L. Burgess et al. · Journal of Medicinal Chemistry · 2010 · 108 citations · Full text

Aurora B/c Kinase, Chemoprevention Strategy, Molecular Biology +21

Yb(OTf)3-catalyzed cyclization of an N-silylenamine with 2-methylene-1,3-cyclohexanedione to afford a 7,8-dihydroquinolin-5(6H)-one derivative and its application to the one-pot conversion to a 2,3,5-trisubstituted quinoline derivative

Norio Sakai, Daisuke Aoki, Toshihiro Hamajima et al. · Tetrahedron Letters · 2006 · 47 citations

Heterocyclic, 2,3,5-Trisubstituted Quinoline Derivative, Organic Chemistry +8

4-Hydroxypyridazin-3(2<i>H</i>)-one Derivatives as Novel<scp>d</scp>-Amino Acid Oxidase Inhibitors

Takeshi Hondo, Masaichi Warizaya, Tatsuya Niimi et al. · Journal of Medicinal Chemistry · 2013 · 44 citations · Full text

Knowledge-based design of 7-azaindoles as selective B-Raf inhibitors

Jun Tang, Toshihiro Hamajima, Masato Nakano et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 35 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase

Samarjit Patnaik, Kirk L. Stevens, Roseanne Gerding et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 26 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +7