Sheena McGowan

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 441 citations · Full text

Drug Target, Bioorganic Chemistry, Antiparasitic Agent +17

Structural basis for the inhibition of the essential <i>Plasmodium falciparum</i> M1 neutral aminopeptidase

Sheena McGowan, Corrine J. Porter, Jonathan Lowther et al. · Proceedings of the National Academy of Sciences · 2009 · 152 citations · Full text

Protein Function, Amino Acids, Biochemistry +14

Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases

Michael B. Harbut, Geetha Velmourougane, Seema Dalal et al. · Proceedings of the National Academy of Sciences · 2011 · 140 citations · Full text

Drug Target, Malaria M1-, Biomolecular Structure Prediction +16

The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates

Ruth M. Kennan, Wilson Wong, Om P. Dhungyel et al. · PLoS Pathogens · 2010 · 121 citations · Full text

Protein Secretion, Protein Assembly, Molecular Biology +17

X-ray crystal structure of the streptococcal specific phage lysin PlyC

Sheena McGowan, Ashley M. Buckle, M S Mitchell et al. · Proceedings of the National Academy of Sciences · 2012 · 99 citations · Full text

Virus Egress, Protein Assembly, Biochemistry +10