Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation

Yun Zhang, Yongzhi Qiu, Aaron T. Blanchard, +5

Proceedings of the National Academy of Sciences

Proteinlipid InteractionEngineeringIntegrin TensionCytoskeletonMechanotransduction +21

Live-cell super-resolved PAINT imaging of piconewton cellular traction forces

Joshua M. Brockman, Hanquan Su, Aaron T. Blanchard, +16

Nature Methods

EngineeringMicroscopyBiomedical ImagingCell BiomechanicsCell Biophysics +5

Mapping the 3D orientation of piconewton integrin traction forces

Joshua M. Brockman, Aaron T. Blanchard, Victor Pui‐Yan, +7

Nature Methods

MechanobiologyEngineeringMechanicsMechanical EngineeringBiomechanics +5

Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces

Palash Dutta, Yun Zhang, Aaron T. Blanchard, +6

Nano Letters

EngineeringForce-sensing ProbesDna AnalysisMolecular BiologyBiofabrication +18

The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation

Victor Pui‐Yan, Yuesong Hu, Anna Kellner, +6

Science Advances

Emerging uses of DNA mechanical devices

Aaron T. Blanchard, Khalid Salaita

Science

EngineeringDna Mechanical DevicesDna AnalysisMolecular BiologyBiofabrication +15

Tunable DNA Origami Motors Translocate Ballistically Over μm Distances at nm/s Speeds

Alisina Bazrafshan, Travis A. Meyer, Hanquan Su, +6

Angewandte Chemie International Edition

EngineeringDna AnalysisMolecular BiologyBiofabricationBiological Computing +17

EGFR activation attenuates the mechanical threshold for integrin tension and focal adhesion formation

Tejeshwar C. Rao, Victor Pui‐Yan, Aaron T. Blanchard, +4

Journal of Cell Science

Dynamic swelling behavior of interpenetrating polymer networks in response to temperature and pH

Brandon V. Slaughter, Aaron T. Blanchard, Katie F. Maass, +1

Journal of Applied Polymer Science

Tissue EngineeringEngineeringIonic PolymersSmart PolymerResponsive Polymers +18

Rapid kinetic fingerprinting of single nucleic acid molecules by a FRET-based dynamic nanosensor

K. L. Khanna, Shankar Mandal, Aaron T. Blanchard, +3

Biosensors and Bioelectronics

Dna NanotechnologyNanosensorsSingle Molecule BiophysicsNatural SciencesRapid Kinetic Fingerprinting +7