Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis

Nam Chu, Antonieta L. Salguero, Albert Z. Liu, +9

Cell

Signal TransductionSignaling PathwayNatural SciencesReceptor Tyrosine KinaseProtein Kinase +7

The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling

Nam Chu, Thibault Viennet, Hwan Bae, +4

eLife

Molecular RegulationMolecular BiologyTumor BiologySignaling PathwayStructural Determinants +19

Enzyme-catalyzed expressed protein ligation

Samuel Henager, Nam Chu, Zan Chen, +5

Nature Methods

BiochemistryProtein FoldingBiocatalysisNatural SciencesEnzyme Catalysis +4

A C-terminal Membrane Anchor Affects the Interactions of Prion Proteins with Lipid Membranes

Nam Chu, Waheed Shabbir, Erin Bove‐Fenderson, +4

Journal of Biological Chemistry

Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics

Minsun Cha, Lin Lin, Grace Hui Ting Yeo, +16

PH domain-mediated autoinhibition and oncogenic activation of Akt

Hwan Bae, Thibault Viennet, Eunyoung Park, +5

eLife

Honey bee odorant-binding protein 14: effects on thermal stability upon odorant binding revealed by FT-IR spectroscopy and CD measurements

Andreas Schwaighofer, Caroline Kotlowski, Can Araman, +7

European Biophysics Journal

BiochemistryOdorant-binding Protein 14Cd MeasurementsThermal StabilityBiophysics

The protein kinase Akt acts as a coat adaptor in endocytic recycling

Jia‐Wei Hsu, Ming Bai, Kunhua Li, +6

Nature Cell Biology

Coat AdaptorProtein FunctionSignal TransductionMedicineNatural Sciences +10

Protein immobilization on liposomes and lipid‐coated nanoparticles by protein <i>trans</i>‐splicing

Nam Chu, Diana Olschewski, R. Seidel, +4

Journal of Peptide Science

NanoparticlesEfficient ImmobilizationEngineeringPeptide EngineeringMolecular Biology +15

Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications

Antonieta L. Salguero, Maggie Chen, Aaron T. Balana, +10

ACS Chemical Biology

Molecular RegulationCellular PhysiologyTumor BiologyProtein ExpressionCell Regulation +16