Lauren D. Hagler

Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1

Ju‐Yeon Lee, Yugang Bai, Ullas V. Chembazhi et al. · Proceedings of the National Academy of Sciences · 2019 · 48 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17

Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA

Ching‐Ming Chien, Pei-Ching Wu, Roshan Satange et al. · Journal of the American Chemical Society · 2020 · 38 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +13

Integrating Display and Delivery Functionality with a Cell Penetrating Peptide Mimic as a Scaffold for Intracellular Multivalent Multitargeting

Yugang Bai, Lien Nguyen, Ziyuan Song et al. · Journal of the American Chemical Society · 2016 · 30 citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +17

A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4

Christoph Sadée, Lauren D. Hagler, Winston R. Becker et al. · Nature Communications · 2022 · 19 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Development of novel macrocyclic small molecules that target CTG trinucleotide repeats

Julio F. Serrano, Ju‐Yeon Lee, L. Daniel Curet et al. · Bioorganic & Medicinal Chemistry · 2019 · 14 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +12