Kevin W. Hallgren - Concepedia

Author

Kevin W. Hallgren

Cleveland Clinic Lerner College of Medicine

Also Known As

K. W. Hallgren, Kevin Hallgren, Kevin W Hallgren, Kevin W. Hallgren

Publications

638

Citations

H-Index

Concepts

All Affiliations

Cleveland Clinic Lerner College of Medicine Cleveland Clinic Case Western Reserve University Case Comprehensive Cancer Center

About

Kevin W. Hallgren is an author at Cleveland Clinic Lerner College of Medicine specializing in natural sciences, medicine, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	229
2	Natural Sciences	4	4	229
3	Biochemistry	2	2	102
4	Biology	2	2	127
5	Chemical Biology	1	1	78

Kevin W. Hallgren

Publications

624

Citations

H-Index

Page 1

	Year	Citations
Mutations in the GGCX and ABCC6 Genes in a Family with Pseudoxanthoma Elasticum-Like Phenotypes Qiaoli Li, Dorothy K. Grange, Nicole L. Armstrong, Journal of Investigative Dermatology BiologySomatic VariantGenetic DisorderNatural SciencesGenetics	2008	106
Novel Insight into the Mechanism of the Vitamin K Oxidoreductase (VKOR) Mark A. Rishavy, Aisulu Usubalieva, Kevin W. Hallgren, Journal of Biological Chemistry Chemical BiologyReductive StressVitamin K EpoxideNovel InsightBiochemistry	2010	78
Carboxylase Overexpression Effects Full Carboxylation but Poor Release and Secretion of Factor IX: Implications for the Release of Vitamin K-Dependent Proteins Kevin W. Hallgren, Eric Hommema, Beth A. McNally, Biochemistry	2002	53
r-VKORC1 Expression in Factor IX BHK Cells Increases the Extent of Factor IX Carboxylation but Is Limited by Saturation of Another Carboxylation Component or by a Shift in the Rate-Limiting Step Kevin W. Hallgren, Wen Qian, Anna V. Yakubenko, Biochemistry	2006	48
Compound heterozygosity of novel missense mutations in the gamma-glutamyl-carboxylase gene causes hereditary combined vitamin K–dependent coagulation factor deficiency Dhouha Darghouth, Kevin W. Hallgren, Rebecca L. Shtofman, Blood	2006	45
The Vitamin K Oxidoreductase Is a Multimer That Efficiently Reduces Vitamin K Epoxide to Hydroquinone to Allow Vitamin K-dependent Protein Carboxylation Mark A. Rishavy, Kevin W. Hallgren, Lee A. Wilson, Journal of Biological Chemistry	2013	43
Brønsted Analysis Reveals Lys218 as the Carboxylase Active Site Base That Deprotonates Vitamin K Hydroquinone To Initiate Vitamin K-Dependent Protein Carboxylation Mark A. Rishavy, Kevin W. Hallgren, Anna V. Yakubenko, Biochemistry	2006	42
A new model for vitamin K-dependent carboxylation: The catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine Mark A. Rishavy, B. Nirmala Pudota, Kevin W. Hallgren, Proceedings of the National Academy of Sciences	2004	39
Identification of the vitamin K-dependent carboxylase active site: Cys-99 and Cys-450 are required for both epoxidation and carboxylation B. Nirmala Pudota, Masaru Miyagi, Kevin W. Hallgren, Proceedings of the National Academy of Sciences	2000	36
Identification of Sequences within the γ-Carboxylase That Represent a Novel Contact Site with Vitamin K-dependent Proteins and That Are Required for Activity B. Nirmala Pudota, Eric Hommema, Kevin W. Hallgren, Journal of Biological Chemistry	2001	35

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