Concepedia
Statistics
Publications
16
Citations
671
H-Index
14
Active since
1989
Affiliations
New Frontier(Current)
Molecular Discovery (United Kingdom)
GlaxoSmithKline (United Kingdom)
GlaxoSmithKline (United States)
South College
C. S. V. HOUGE‐FRYDRYCH is an author at New Frontier specializing in enzyme inhibition, aminoacyl-trna synthetases, and enzymology.
Publications per year
1989–2003
Crystal structure of <i>Staphylococcus aureus</i> tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors
Xiayang Qiu, Cheryl A. Janson, Ward W. Smith et al. · Protein Science · 2001 · 221 citations · Full text
Life Sciences, Biochemistry, Microbiology +17
A Potent Seryl tRNA Synthetase Inhibitor SB-217452 Isolated from a Streptomyces species.
Anna L. Stefanska, Mark Fulston, C. S. V. HOUGE‐FRYDRYCH et al. · The Journal of Antibiotics · 2000 · 93 citations · Full text
Life Sciences, Biochemistry, Microbiology +5
SB-203207 and SB-203208, Too Novel Isoleucyl tRNA Synthetase Inhibitors from a Streptomyces sp. II. Structure Determination.
C. S. V. HOUGE‐FRYDRYCH, Martin L. Gilpin, Peter W. Skett et al. · The Journal of Antibiotics · 2000 · 50 citations · Full text
Life Sciences, Biochemistry, Microbiology +12
Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis
Derek R. Buckle, Ashley Fenwick, C. S. V. HOUGE‐FRYDRYCH et al. · Journal of Medicinal Chemistry · 1990 · 40 citations
Medicine, Chemistry, Pharmacology +6
Relaxant activity of 6-cyano-2,2-dimethyl-2H-1-benzopyran-4-carboxamides and -thiocarboxamides and their analogs in guinea pig trachealis
J R Arch, Derek R. Buckle, H. PARR‐DOBRZANSKI et al. · Journal of Medicinal Chemistry · 1991 · 40 citations
Medicine, Chemistry, Pharmacology +5
1–5 of 16