Susan Adel

Evolutionary alteration of ALOX15 specificity optimizes the biosynthesis of antiinflammatory and proresolving lipoxins

Susan Adel, Felix Karst, Àngels González‐Lafont et al. · Proceedings of the National Academy of Sciences · 2016 · 69 citations · Full text

Conversion of pro-inflammatory murine Alox5 into an anti-inflammatory 15S-lipoxygenating enzyme by multiple mutations of sequence determinants

Katharina Hofheinz, Kumar Reddy Kakularam, Susan Adel et al. · Archives of Biochemistry and Biophysics · 2012 · 32 citations

Inflammation, Aldehyde Dehydrogenase, Multiple Mutations +5

The lipoxygenase pathway in zebrafish. Expression and characterization of zebrafish ALOX5 and comparison with its human ortholog

Susan Adel, Dagmar Heydeck, Hartmut Kühn et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2015 · 25 citations

Lipoxygenase Pathway, Developmental Biology, Oxysterol +11

Leukotriene signaling in the extinct human subspecies Homo denisovan and Homo neanderthalensis. Structural and functional comparison with Homo sapiens

Susan Adel, Kumar Reddy Kakularam, Thomas Horn et al. · Archives of Biochemistry and Biophysics · 2014 · 16 citations

Biology, Signal Transduction, Homo Neanderthalensis +6

Probing conformational changes in lipoxygenases upon membrane binding: Fine-tuning by the active site inhibitor ETYA

Almerinda Di Venere, Eleonora Nicolai, Igor Ivanov et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2013 · 15 citations

Proteinlipid Interaction, Biochemistry, Natural Sciences +6