Complex pectin metabolism by gut bacteria reveals novel catalytic functions

Didier Ndeh, Artur Rogowski, Alan Cartmell, +21

Nature

BiochemistryComplex Pectin MetabolismBioenergeticsMicrobial ProteomicsMicrobiology +4

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

Fiona Cuskin, Elisabeth C. Lowe, Max J. Temple, +29

Nature

BiologyYeast MannanSelfish MechanismDysbiosisHuman Gut Bacteroidetes +8

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides

Ana S. Luís, Jonathon A. Briggs, Xiaoyang Zhang, +18

Nature Microbiology

Coordinated Enzyme PathwaysDietary Pectic GlycansBiochemistryFood DigestionGlycobiology +7

Improved prevention of moderately emetogenic chemotherapy‐induced nausea and vomiting with palonosetron, a pharmacologically novel 5‐HT₃ receptor antagonist

Peter D. Eisenberg, Jazmin Figueroa‐Vadillo, Rosalio Zamora, +5

Cancer

A single sulfatase is required to access colonic mucin by a gut bacterium

Ana S. Luís, Chunsheng Jin, Gabriel Vasconcelos Pereira, +18

Nature

Gut BacteriumDysbiosisBiochemistryAccess Colonic MucinBacteriology +4

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

Alan Cartmell, José Muñoz-Muñoz, Jonathon A. Briggs, +16

Nature Microbiology

Microbial DiversityBacteroides Thetaiotaomicron ConfersGram-negative BacteriologyArabinogalactan DegradationBacteriology +7

How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans

Alan Cartmell, Elisabeth C. Lowe, Arnaud Baslé, +10

Proceedings of the National Academy of Sciences

Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus

Didier Ndeh, Arnaud Baslé, Henrik Strahl, +5

Nature Communications

Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis

Joana L. A. Brás, Alan Cartmell, Ana Luı́sa Carvalho, +10

Proceedings of the National Academy of Sciences

The Structure and Function of an Arabinan-specific α-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases

Alan Cartmell, Lauren S. McKee, María J. Peña, +8

Journal of Biological Chemistry