Alessandra Vecchié

Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19

Roberto Caricchio, Antonio Abbate, Jamie Meng et al. · JAMA · 2021 · 166 citations · Full text

Medicine, Immunology, Pharmacotherapy +11

Phase 1B, Randomized, Double-Blinded, Dose Escalation, Single-Center, Repeat Dose Safety and Pharmacodynamics Study of the Oral NLRP3 Inhibitor Dapansutrile in Subjects With NYHA II–III Systolic Heart Failure

George F. Wohlford, Benjamín Van Tassell, Hayley Billingsley et al. · Journal of Cardiovascular Pharmacology · 2020 · 159 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

The Role of NLRP3 Inflammasome in Pericarditis

Adolfo G Mauro, Aldo Bonaventura, Alessandra Vecchié et al. · JACC Basic to Translational Science · 2021 · 102 citations · Full text

Medicine, Cardiology, Immunology +17

The effects of canagliflozin compared to sitagliptin on cardiorespiratory fitness in type 2 diabetes mellitus and heart failure with reduced ejection fraction: The <scp>CANA‐HF</scp> study

Salvatore Carbone, Hayley Billingsley, Justin M. Canada et al. · Diabetes/Metabolism Research and Reviews · 2020 · 76 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial

Paul Cremer, Antonio Abbate, Kristin Hudock et al. · The Lancet Rheumatology · 2021 · 69 citations · Full text

Life Sciences, Clinical Sciences, Immunology +17