Satoshi Sakami

(3R)-3-Amino-4-(2,4,5-trifluorophenyl)-N-{4-[6-(2-methoxyethoxy)benzothiazol-2-yl]tetrahydropyran-4-yl}butanamide as a potent dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

A. Nitta, H. Fujii, Satoshi Sakami et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 35 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Medicine +10

Design and synthesis of a metabolically stable and potent antitussive agent, a novel δ opioid receptor antagonist, TRK-851

Satoshi Sakami, Koji Kawai, Masayuki Maeda et al. · Bioorganic & Medicinal Chemistry · 2008 · 27 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +7

Structure−Antitussive Activity Relationships of Naltrindole Derivatives. Identification of Novel and Potent Antitussive Agents

Satoshi Sakami, Masayuki Maeda, Koji Kawai et al. · Journal of Medicinal Chemistry · 2008 · 24 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Experimental Pharmacology +21

Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors

A. Nitta, H. Fujii, Satoshi Sakami et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 21 citations · Full text

Medicinal Chemistry, Novel Series, Biochemistry +9

HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models

Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 18 citations