Fred C. Lam

β‐Amyloid efflux mediated by p‐glycoprotein

Fred C. Lam, Ronghua Liu, Peihua Lu et al. · Journal of Neurochemistry · 2001 · 375 citations

Life Sciences, Neurobiology, Neuroscience +15

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury

Bo Hu, Chengcheng Jin, Huabing Li et al. · Science · 2016 · 371 citations · Full text

Medicine, Immunology, Molecular Biology +17

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

Scott Floyd, Michael E. Pacold, Qiuying Huang et al. · Nature · 2013 · 332 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles

Fred C. Lam, Stephen W. Morton, Jeffrey Wyckoff et al. · Nature Communications · 2018 · 326 citations · Full text

Pharmacy, Oncology, Pharmacology +17

BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage

Fred C. Lam, Yi Wen Kong, Qiuying Huang et al. · Nature Communications · 2020 · 149 citations · Full text

Life Sciences, Molecular Biology, Oncology +17