Marie-Claire Letellier

Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy

Bruno Gomes, Grégory Driessens, Derek W. Bartlett et al. · Molecular Cancer Therapeutics · 2018 · 83 citations · Full text

Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers

Delia Hoffmann, Tereza Dvořáková, Vincent Stroobant et al. · Cancer Immunology Research · 2019 · 54 citations · Full text

Abstract 4863: PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors

Joseph R. Tumang, Bruno Gomes, Martin Wythes et al. · Cancer Research · 2016 · 25 citations

Immune Regulation, Immunology, Immunologic Mechanism +20

Inhibition of ENT1 relieves intracellular adenosine-mediated T cell suppression in cancer

Theodore J. Sanders, Christopher S. Nabel, Margreet Brouwer et al. · Nature Immunology · 2025 · 19 citations · Full text