Brent J. Guppy

An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

Derek M. van Pel, Irene Barrett, Yoko Shimizu et al. · PLoS Genetics · 2013 · 89 citations · Full text

Drug Target, Anticancer Therapeutic Development, Cancer Biology +16

Synthetic Genetic Targeting of Genome Instability in Cancer

Babu V. Sajesh, Brent J. Guppy, Kirk J. McManus · Cancers · 2013 · 35 citations · Full text

Synthetic Dosage Lethality, Medicine, Cancer Cell Biology +12

Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells

Brent J. Guppy, Kirk J. McManus · Genetics · 2014 · 31 citations · Full text

A single nucleotide polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated north American cannabis

Philippe Henry, Surender Khatodia, Karan Kapoor et al. · Journal of Cannabis Research · 2020 · 28 citations · Full text

Plant Genetics, Single Nucleotide Polymorphism, Botany +30

Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression

Jamie Zagozewski, Stephanie Borlase, Brent J. Guppy et al. · Communications Biology · 2022 · 21 citations · Full text