Smit Shah

Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms

Neha Bhagwat, Priya Koppikar, Matthew D. Keller et al. · Blood · 2014 · 109 citations

Medicine, Hematology, Pharmacology +12

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

Maria Carmen Inda, Suhasini Joshi, Tai Wang et al. · Nature Communications · 2020 · 87 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Tony Taldone, Pallav D. Patel, Maulik Patel et al. · Journal of Medicinal Chemistry · 2013 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Hardik Patel, Pallav D. Patel, Stefan O. Ochiana et al. · Journal of Medicinal Chemistry · 2015 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

Srikanth Ambati, Eloisi Caldas Lopes, Kohji Kosugi et al. · Molecular Oncology · 2013 · 64 citations · Full text

Medicine, Oncology, Pharmacology +17