Ryokichi Koyama

In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)

Nobumichi Ohoka, Keiichiro Okuhira, Masahiro Ito et al. · Journal of Biological Chemistry · 2017 · 237 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands

Norihito Shibata, Katsunori Nagai, Yoko Morita et al. · Journal of Medicinal Chemistry · 2017 · 143 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

Nobumichi Ohoka, Yoko Morita, Katsunori Nagai et al. · Journal of Biological Chemistry · 2018 · 103 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals

Yusuke Moritoh, Shinichi Abe, Hiroki Akiyama et al. · Nature Communications · 2021 · 80 citations · Full text

Life Sciences, Biochemistry, Physiology +16

A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine

Tomohiro Kodera, Sergey V. Smirnov, Natalya N. Samsonova et al. · Biochemical and Biophysical Research Communications · 2009 · 77 citations

Life Sciences, Biochemistry, Enzymology +9