Hiroaki Shimada

Inhibition of Methotrexate Uptake <i>via</i> Organic Anion Transporters OAT1 and OAT3 by Glucuronides of Nonsteroidal Anti-inflammatory Drugs

Masahiro Iwaki, Hiroaki Shimada, Yuri Irino et al. · Biological and Pharmaceutical Bulletin · 2017 · 42 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Prostaglandin Transporter OATP2A1/<i>SLCO2A1</i> Is Essential for Body Temperature Regulation during Fever

Yoshinobu Nakamura, Takeo Nakanishi, Hiroaki Shimada et al. · Journal of Neuroscience · 2018 · 40 citations · Full text

Life Sciences, Biochemistry, Physiology +13

OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion

Hiroaki Shimada, Yoshinobu Nakamura, Takeo Nakanishi et al. · Biochemical Pharmacology · 2015 · 36 citations

Life Sciences, Cell Biology, Molecular Biology +6

A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer

Takeo Nakanishi, Yasuhiro Ohno, Rika Aotani et al. · Scientific Reports · 2017 · 31 citations · Full text

Medicine, Cancer Biology, Oncology +14

Increased penetration of diphenhydramine in brain via proton-coupled organic cation antiporter in rats with lipopolysaccharide-induced inflammation

Atsushi Kawase, Taihei Chuma, Kota Irie et al. · Brain Behavior & Immunity - Health · 2020 · 24 citations · Full text

Medicine, Neuroscience, Pharmacology +17