Christopher Negron - Concepedia

Author

Christopher Negron

Schrodinger (United States)ORCID

Also Known As

Christopher Negron

Publications

563

Citations

H-Index

Concepts

All Affiliations

Schrodinger (United States)City College of New York Alexion Pharmaceuticals (United States)Massachusetts Institute of Technology Memorial Sloan Kettering Cancer Center

About

Christopher Negron is an author at Schrodinger (United States) specializing in molecular biology, medicine, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	170
2	Natural Sciences	5	5	225
3	Biochemistry	3	3	190
4	Engineering	2	2	87
5	Health Sciences	1	1	17

Christopher Negron

Publications

563

Citations

H-Index

Page 1

	Year	Citations
Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability—Large-Scale Validation of MD-Based Relative Free Energy Calculations Thomas Steinbrecher, Chongkai Zhu, Lingle Wang, Journal of Molecular Biology Protein ChemistryBiochemistryProtein FoldingNatural SciencesProtein Evolution	2016	113
Relative Binding Affinity Prediction of Charge-Changing Sequence Mutations with FEP in Protein–Protein Interfaces Anthony Clark, Christopher Negron, Kevin Hauser, Journal of Molecular Biology	2019	104
Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations Kevin Hauser, Christopher Negron, Steven K. Albanese, Communications Biology	2018	100
A Set of Computationally Designed Orthogonal Antiparallel Homodimers that Expands the Synthetic Coiled-Coil Toolkit Christopher Negron, Amy E. Keating Journal of the American Chemical Society EngineeringCoiled-coil Drug DeliveryProtein AssemblyProtein FoldingPeptide Engineering	2014	64
Large‐scale in vitro functional testing and novel variant scoring via protein modeling provide insights into alkaline phosphatase activity in hypophosphatasia Guillermo del Angel, John Reynders, Christopher Negron, Human Mutation GeneticsMolecular BiologyDisease Gene IdentificationGenomicsResidual Activity	2020	54
Manipulating Cofactor Binding Thermodynamics in an Artificial Oxygen Transport Protein Lei Zhang, J. L. Ross Anderson, Ismail Y. Ahmed, Biochemistry Distal HistidineProtein AssemblyMolecular BiologyRedox BiologyHeme Trafficking	2011	23
Multistate Protein Design Using CLEVER and CLASSY Christopher Negron, Amy E. Keating Methods in enzymology on CD-ROM/Methods in enzymology EngineeringProtein FoldingNatural SciencesComputational BiologyMolecular Biology	2013	23
Geometric constraints for porphyrin binding in helical protein binding sites Christopher Negron, Christian Fufezan, Ronald L. Koder Proteins Structure Function and Bioinformatics	2008	22
Design principles for chlorophyll‐binding sites in helical proteins Paula Braun, Eran Goldberg, Christopher Negron, Proteins Structure Function and Bioinformatics	2010	21
Predicting mutations deleterious to function in beta-lactamase TEM1 using MM-GBSA Christopher Negron, David A. Pearlman, Guillermo del Angel PLoS ONE Missense MutationsMolecular BiologyDrug ResistanceBeta-lactamase Tem1Biostatistics	2019	17

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