H. Michael Shepard

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

Michael A. Jacobetz, Derek Chan, Tashinga E. Bapiro et al. · Gut · 2012 · 1.1K citations · Full text

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

Clifford J. Whatcott, Caroline H. Diep, Ping Jiang et al. · Clinical Cancer Research · 2015 · 605 citations · Full text

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer

Sunil R. Hingorani, William Proctor Harris, J. Thaddeus Beck et al. · Clinical Cancer Research · 2016 · 317 citations · Full text

Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

Curtis B. Thompson, H. Michael Shepard, P M O'Connor et al. · Molecular Cancer Therapeutics · 2010 · 291 citations

Tissue Engineering, Engineering, Tumor Innervation +22

A recombinant human enzyme for enhanced interstitial transport of therapeutics

Louis H. Bookbinder, Anthony Hofer, Michael F. Haller et al. · Journal of Controlled Release · 2006 · 259 citations

Cell-based Drug Delivery, Biochemistry, Medicine +10