Julia Frederick

Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression

Amin Abedini, Jonathan Levinsohn, Konstantin A. Klötzer et al. · Nature Genetics · 2024 · 148 citations · Full text

Medicine, Cell Biology, Nephrology +17

Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

Amin Abedini, Jonathan Levinsohn, Konstantin A. Klötzer et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 42 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists

Amin Abedini, Junnan Wu, Konstantin A. Klötzer et al. · Journal of Clinical Investigation · 2023 · 40 citations · Full text

Medicine, Nephrology, Pharmacology +17

Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution

Michael S. Balzer, Mira Pavkovic, Julia Frederick et al. · Cell Reports Medicine · 2023 · 33 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice

Ya‐Wen Yang, Bibek Poudel, Julia Frederick et al. · Molecular Therapy · 2022 · 15 citations · Full text

Medicine, Genetics, Nephrology +13