Inflammation and tumor progression: signaling pathways and targeted intervention

Huakan Zhao, Lei Wu, Guifang Yan, +4

Signal Transduction and Targeted Therapy

RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis

Lei Wu, Xiao Zhang, Lu Zheng, +15

Cancer Immunology Research

Tumor-associated MacrophagesApoptosisImmunologyPathologyMetabolic Remodeling +16

A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell–Potentiated Colorectal Carcinogenesis

Guifang Yan, Huakan Zhao, Qi Zhang, +12

Cancer Research

FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation

Huakan Zhao, Fenglin Lv, Guizhao Liang, +6

Oncotarget

Fgf19-induced Emt ProcessHepatocellular Carcinoma CellsPathologyCancer BiologyTumor Biology +17

STIM1 is a metabolic checkpoint regulating the invasion and metastasis of hepatocellular carcinoma

Huakan Zhao, Guifang Yan, Lu Zheng, +14

Theranostics

FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4–GSK3β–Nrf2 Signaling

Yong Teng, Huakan Zhao, Lixia Gao, +3

Cancer Research

The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

Yiguo Zhang, Shaojun Li, Yuancai Xiang, +3

Scientific Reports

An NAD+-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39

Ling Dong, Le Yu, Hui Li, +7

iScience

FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells

Jingchun Wang, Huakan Zhao, Lu Zheng, +18

Theranostics

Microbiota-derived SSL6 enhances the sensitivity of hepatocellular carcinoma to sorafenib by down-regulating glycolysis

Xiao Zhang, Lei Wu, Yanquan Xu, +11

Cancer Letters

HepatologyOncogenic AgentMedicineLiver PhysiologyMicrobiota-derived Ssl6 +8