Hue-Kian Oh

Conformational Change in Human DNA Repair Enzyme <i>O</i>⁶-Methylguanine-DNA Methyltransferase upon Alkylation of Its Active Site by SN1 (Indirect-Acting) and SN2 (Direct-Acting) Alkylating Agents:  Breaking a “Salt-Link”?

Hue-Kian Oh, Alvin K.-C. Teo, Rahmen B. Ali et al. · Biochemistry · 1996 · 35 citations

Cellular Mgmt, “ Salt-link ”, Molecular Biology +17

Implication of Localization of Human DNA Repair Enzyme <i>O</i>⁶-Methylguanine-DNA Methyltransferase at Active Transcription Sites in Transcription-Repair Coupling of the Mutagenic <i>O</i>⁶-Methylguanine Lesion

Rahmen B. Ali, Alvin K.-C. Teo, Hue-Kian Oh et al. · Molecular and Cellular Biology · 1998 · 35 citations · Full text

Dna Damage, Active Transcription Sites, Epigenetic Change +22

Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer.

Hue-Kian Oh, Angie Lay-Keng Tan, Kakoli Das et al. · 2011 · 20 citations

Tumor Biology, Gastrointestinal Oncology, Medicine +12

A method for simultaneous identification of human active and active-site alkylated O6-methylguanine-DNA methyltransferase and its possible application for monitoring human exposure to alkylating carcinogens.

Teck-Choon Ayi, Hue-Kian Oh, Timothy K-Y. Lee et al. · PubMed · 1994 · 17 citations

Induced Mgmt Deficiency, Chemoprevention Strategy, Molecular Biology +22