IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma

Erik Ladomersky, Lijie Zhai, Alicia Lenzen, +18

Clinical Cancer Research

Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, +12

Clinical Cancer Research

The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma

Erik Ladomersky, Denise Scholtens, Masha Kocherginsky, +11

Frontiers in Pharmacology

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

Erik Ladomersky, Lijie Zhai, Kristen L. Lauing, +22

Clinical Cancer Research

Aggrecan is required for growth plate cytoarchitecture and differentiation

Kristen L. Lauing, Mauricio Cortes, Miriam S. Domowicz, +3

Developmental Biology

Cell DivisionHuman GrowthGrowth Plate CytoarchitectureMorphogenesisCell Proliferation +4

The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy

Lijie Zhai, Mahua Dey, Kristen L. Lauing, +11

Journal of Clinical Neuroscience

Neuro-oncologyPrognostic ToolGliomaMedicinePharmacology +9

Binge alcohol treatment of adolescent rats followed by alcohol abstinence is associated with site-specific differences in bone loss and incomplete recovery of bone mass and strength

Kristen L. Lauing, Ryan Himes, Matthew Rachwalski, +2

Alcohol

Substance AbuseBone LossSubstance UseBone HealthBinge Alcohol Treatment +10

Binge Alcohol-Induced Bone Damage is Accompanied by Differential Expression of Bone Remodeling-Related Genes in Rat Vertebral Bone

John J. Callaci, Ryan Himes, Kristen L. Lauing, +2

Calcified Tissue International

Bone DiseaseDevelopmental BiologyBone Remodeling-related GenesDifferential ExpressionRat Vertebral Bone +7

Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma

Lijie Zhai, Erik Ladomersky, Carlos R. Dostal, +8

Brain Behavior and Immunity

Ctla-4/pd-l1 InhibitionNeuro-oncologyNon-tumor Cell Ido1MedicineImmune Checkpoint Inhibitor +7

Acute Alcohol Exposure Impairs Fracture Healing and Deregulates β‐Catenin Signaling in the Fracture Callus

Kristen L. Lauing, Philip M. Roper, Rachel K. Nauer, +1

Alcoholism Clinical and Experimental Research