Jaco A. C. van Bruggen

Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy

Jaco A. C. van Bruggen, Anne W. J. Martens, Joseph A. Fraietta et al. · Blood · 2019 · 182 citations · Full text

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

Zhenghao Chen, Helga Simon‐Molas, Gaspard Cretenet et al. · Blood · 2022 · 42 citations · Full text

Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

Johan M. S. van der Schoot, Felix L. Fennemann, Michael Valente et al. · Science Advances · 2019 · 24 citations · Full text

Engineering, Genetics, Immunology +20

CD40 signaling instructs chronic lymphocytic leukemia cells to attract monocytes via the CCR2 axis

Martijn H.A. van Attekum, Jaco A. C. van Bruggen, Erik Slinger et al. · Haematologica · 2017 · 18 citations · Full text

Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells

Jaco A. C. van Bruggen, Gerritje J. W. van der Windt, Mels Hoogendoorn et al. · Blood Advances · 2022 · 16 citations · Full text