Concepedia

Pablo Alcón

PA

8

Publications

835

Citations

8

H-Index

2017

Active since

Affiliations

MRC Laboratory of Molecular Biology(Current)

Technische Universität Berlin

Novo Nordisk Foundation

University of Copenhagen

Wellcome Centre for Cell Biology

Pablo Alcón is an author at MRC Laboratory of Molecular Biology specializing in molecular biology, medicine, and molecular genetics.

Top concepts

Molecular BiologyMedicineGeneticsMolecular GeneticsDna ReplicationNatural SciencesGenome InstabilityStructural BiologyBiomolecular EngineeringCrispr

Publications per year

2017–2024

8

Publications

8

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

Stefano Stella, Pablo Mesa, Johannes Thomsen et al. · Cell · 2018 · 269 citations · Full text

Engineering, Molecular Biology, Synthetic Biology +7

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

Stefano Stella, Pablo Alcón, Guillermo Montoya · Nature · 2017 · 227 citations

Molecular Research, Structural Bioinformatics, Natural Sciences +6

Structure of the Fanconi anaemia monoubiquitin ligase complex

Shabih Shakeel, Eeson Rajendra, Pablo Alcón et al. · Nature · 2019 · 125 citations · Full text

Protein Function, Genetics, Molecular Biology +4

FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Pablo Alcón, Shabih Shakeel, Zhuo A. Chen et al. · Nature Structural & Molecular Biology · 2020 · 120 citations · Full text

Genome Instability, Nucleic Acid Chemistry, Genetics +4

The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

Tamara Sijacki, Pablo Alcón, Zhuo A. Chen et al. · Nature Structural & Molecular Biology · 2022 · 27 citations · Full text

Chromatin, Genome Instability, Molecular Regulation +9

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