Tomoko Nishino

Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion

Cristofer Enroth, B.T. Eger, Ken Okamoto et al. · Proceedings of the National Academy of Sciences · 2000 · 718 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

An Extremely Potent Inhibitor of Xanthine Oxidoreductase

Ken Okamoto, B.T. Eger, Tomoko Nishino et al. · Journal of Biological Chemistry · 2003 · 424 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversion by trypsin.

Yoshihiro Amaya, Kimihisa Yamazaki, Masayuki Sato et al. · Journal of Biological Chemistry · 1990 · 276 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase

Tomoko Nishino, Tomoko Nishino, Ken Okamoto et al. · Journal of Biological Chemistry · 2005 · 160 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Identification of two mutations in human xanthine dehydrogenase gene responsible for classical type I xanthinuria.

Kimiyoshi Ichida, Yoshihiro Amaya, Naoyuki Kamatani et al. · Journal of Clinical Investigation · 1997 · 154 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12