Kentaro Uemura

Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

Yuto Unoh, Shota Uehara, Kenji Nakahara et al. · Journal of Medicinal Chemistry · 2022 · 553 citations · Full text

SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells

Michihito Sasaki, Kentaro Uemura, Akihiko Sato et al. · PLoS Pathogens · 2021 · 210 citations · Full text

S Gene Mutations, Sars-cov-2 Variants, Viral Evolution +13

S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters

Michihito Sasaki, Koshiro Tabata, Mai Kishimoto et al. · Science Translational Medicine · 2022 · 91 citations · Full text

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus

Satomi Yamamoto, Takasuke Fukuhara, Chikako Ono et al. · PLoS Pathogens · 2016 · 89 citations · Full text

Hepatitis C Virus, Immunology, Viral Pathogenesis +18

TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein

Mai Kishimoto, Kentaro Uemura, Takao Sanaki et al. · Viruses · 2021 · 87 citations · Full text

Virus Structure, Tmprss13 Activate, Viral Replication +14