Mary Mehlig

Structure−Function Engineering of Interferon-β-1b for Improving Stability, Solubility, Potency, Immunogenicity, and Pharmacokinetic Properties by Site-Selective Mono-PEGylation

Amartya Basu, Karen Yang, Maoliang Wang et al. · Bioconjugate Chemistry · 2006 · 213 citations

Ethylene Glycol, Immunology, Structure−function Engineering +22

Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11–Refractory Model

Puja Sapra, Hong Zhao, Mary Mehlig et al. · Clinical Cancer Research · 2008 · 165 citations · Full text

Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation

Kaiyong Yang, Anirban Basu, Ramesh Chintala et al. · Protein Engineering Design and Selection · 2003 · 118 citations · Full text

Engineering, Protein Assembly, Peptide Engineering +22

Antitumor activity of poly(ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo

Deshan Yu, Ping Peng, S. Dharap et al. · Journal of Controlled Release · 2005 · 116 citations

Tumor Biology, Ethylene Glycol, Oncology +11

Anticancer drug delivery systems: multi-loaded N4-acyl poly(ethylene glycol) prodrugs of ara-C.II. Efficacy in ascites and solid tumors

Yun H. Choe, Cheryl A. Conover, Dee Wu et al. · Journal of Controlled Release · 2002 · 77 citations

Nanomedicine, Ethylene Glycol, Drug Targeting +12