PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury

Chen Shen, Liping Chen, Lizhu Ye, +16

Journal of Hazardous Materials

Acute Lung InjuryInflammationSignal TransductionInflammatory Lung DiseaseLung Deposition +11

Characterization of the interactions between chitosan/whey protein at different conditions

Lizhu Ye, Huibin Chen

Food Science and Technology

Low Amount ChitosanProtein ChemistryEngineeringBiochemistryProtein Folding +13

Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by real ambient particulate matter exposure

Daochuan Li, Chen Shen, Qiong Li, +14

Particle and Fibre Toxicology

Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

Rui Zhang, Chen Shen, Liping Chen, +15

Particle and Fibre Toxicology

Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1

Liping Chen, Ping Guo, Haiyan Zhang, +22

Journal of Biological Chemistry

Determination of tipping point in course of PM2.5 organic extracts-induced malignant transformation by dynamic network biomarkers

Chen Shen, Daochuan Li, Dianke Yu, +12

Journal of Hazardous Materials

Biomarker (Medicine)Chemoprevention StrategyOncogenic AgentMedicineBiomarker Target +6

Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study

Chen Shen, Miao Li, Rui Zhang, +12

Particle and Fibre Toxicology

CpG site-specific methylation as epi-biomarkers for the prediction of health risk in PAHs-exposed populations

Lizhu Ye, Zhini He, Daochuan Li, +15

Journal of Hazardous Materials

Health RiskEnvironmental ExposureGlobal HealthEnvironmental HealthMedicine +11

An integrative analysis of lipidomics and transcriptomics in various mouse brain regions in response to real-ambient PM2.5 exposure

Shuangjian Qin, Huixian Zeng, Qi-Zhen Wu, +13

The Science of The Total Environment

Neurochemical BiomarkersBrain-immune InteractionNeuroprotectionNeuroscienceNeurology +6

Assessing the Effects of Nicotinamide Mononucleotide Supplementation on Pulmonary Inflammation in Male Mice Subchronically Exposed to Ambient Particulate Matter

Rui Zhang, Chen Shen, Ziwei Wang, +12

Environmental Health Perspectives