Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Zunlong Ke, Kun Qu, Mirko Cortese, +13

Nature

Intact VirionsVirus StructureViral EvolutionPathogenesisViral Pathogenesis +6

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

Steffen Klein, Mirko Cortese, Sophie L. Winter, +7

Nature Communications

Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies

Mirko Cortese, Ji-Young Lee, Berati Cerikan, +26

Cell Host & Microbe

Biomedical ImagingViral Structural ProteinCell BiologySubcellular MorphologiesNovel Imaging Method

SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

Christopher J. Neufeldt, Berati Cerikan, Mirko Cortese, +19

Communications Biology

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

Wael Kamel, Marko Noerenberg, Berati Cerikan, +18

Molecular Cell

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle

Anna Płaszczyca, Pietro Scaturro, Christopher J. Neufeldt, +6

PLoS Pathogens

Viral ReplicationDengue VirusImmunologyMolecular BiologyAnalytical Ultracentrifugation +16

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation

Woan-Ing Twu, Ji‐Young Lee, Heeyoung Kim, +5

Cell Reports

Viral ReplicationViral Polymerase MechanismViral PathogenesisAutophagy Machinery FactorsReplication Organelles +14

Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19

Kas Steuten, Heeyoung Kim, John C. Widen, +13

ACS Infectious Diseases

ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly

Christopher J. Neufeldt, Mirko Cortese, Pietro Scaturro, +7

Nature Microbiology

Viral ReplicationMolecular VirologyNatural SciencesPathogenesisVirion Assembly +9

Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation

Keisuke Tabata, Vibhu Prasad, David Paul, +23

Nature Communications