LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

Alessandra Mancini, Sasha Howard, Federica Marelli, +17

JCI Insight

Human GrowthGeneticsLgr4 Deficiency ResultsFemale Reproductive FunctionEmbryology +26

HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes

Sasha Howard, Roberto Oleari, Ariel Poliandri, +11

The Journal of Clinical Endocrinology & Metabolism

Protein Kinase CK2 Subunits Differentially Perturb the Adhesion and Migration of GN11 Cells: A Model of Immature Migrating Neurons

Antonella Lettieri, Christian Borgo, Luca Zanieri, +6

International Journal of Molecular Sciences

Immature Migrating NeuronsProtein Kinase Ck2Cell AdhesionIndividual Ck2 SubunitsCellular Neurobiology +22

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons

Roberto Oleari, Alessia Caramello, Sara Campinoti, +6

Development

A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia

Danielle Whittaker, Roberto Oleari, Louise Gregory, +18

UCL Discovery (University College London)

GeneticsCongenital Hypogonadotropic HypogonadismMolecular GeneticsEpigeneticsPrdm13 Mutation +14

Aortic Gene Expression Profiles Show How ApoA-I Levels Modulate Inflammation, Lysosomal Activity, and Sphingolipid Metabolism in Murine Atherosclerosis

Marco Busnelli, Stefano Manzini, Matteo Chiara, +7

Arteriosclerosis Thrombosis and Vascular Biology

A Novel SEMA3G Mutation in Two Siblings Affected by Syndromic GnRH Deficiency

Roberto Oleari, Valentina Andrè, Antonella Lettieri, +15

Neuroendocrinology

Iron overload induces hypogonadism in male mice via extrahypothalamic mechanisms

Chiara Macchi, Liliana Steffani, Roberto Oleari, +8

Molecular and Cellular Endocrinology

InfertilityAndrologyDevelopmental BiologyFertilityEndocrine Mechanism +11

Anti-Müllerian Hormone, Growth Hormone, and Insulin-Like Growth Factor 1 Modulate the Migratory and Secretory Patterns of GnRH Neurons

Rossella Cannarella, Alyssa Paganoni, Stefania Cicolari, +6

International Journal of Molecular Sciences

Human GrowthNeuroendocrinologyGnrh SecretionReproductive BiologyReproductive Endocrinology +18

SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability

Antonella Lettieri, Roberto Oleari, Marleen H. van den Munkhof, +15

Nature Communications