Fiona Macintyre

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · PubMed · 1997 · 638 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 591 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial

Aung Pyae Phyo, Podjanee Jittamala, François Nosten et al. · The Lancet Infectious Diseases · 2015 · 189 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

Fiona Macintyre, Adoke Yeka, Alfred B. Tiono et al. · BMC Medicine · 2017 · 82 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Adoke Yeka, Rella Zoleko‐Manego, Serge Ouoba et al. · Malaria Journal · 2021 · 59 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16