James L. Hickey

Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I) <i>N</i>-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols

James L. Hickey, Rasha A. Ruhayel, Peter J. Barnard et al. · Journal of the American Chemical Society · 2008 · 583 citations

Pharmacy, Medicinal Chemistry, Oncology +17

Cationic, linear Au(i) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity

Murray V. Baker, Peter J. Barnard, Susan J. Berners‐Price et al. · Dalton Transactions · 2006 · 274 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Oral Treatment with CuII(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Blaine R. Roberts, Nastasia K.-H. Lim, Erin J. McAllum et al. · Journal of Neuroscience · 2014 · 205 citations · Full text

Life Sciences, Neurology, Neuroscience +15

Synthesis and structural characterisation of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin

Murray V. Baker, Peter J. Barnard, Susan J. Berners‐Price et al. · Journal of Organometallic Chemistry · 2005 · 184 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Diacetylbis(N(4)-methylthiosemicarbazonato) Copper(II) (CuII(atsm)) Protects against Peroxynitrite-induced Nitrosative Damage and Prolongs Survival in Amyotrophic Lateral Sclerosis Mouse Model

Cynthia P.W. Soon, Paul S. Donnelly, Bradley J. Turner et al. · Journal of Biological Chemistry · 2011 · 152 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17