Rescuing AAV gene transfer from neutralizing antibodies with an IgG-degrading enzyme

Zachary C. Elmore, Daniel K. Oh, Katherine E. Simon, +2

JCI Insight

Synthetic VirologyImmunologyImmunotherapyAav Gene TransferSynthetic Immunology +19

The membrane associated accessory protein is an adeno-associated viral egress factor

Zachary C. Elmore, L. Patrick Havlik, Daniel K. Oh, +5

Nature Communications

Sumo-dependent substrate targeting of the SUMO protease Ulp1

Zachary C. Elmore, Megan Donaher, Brooke C. Matson, +3

BMC Biology

Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription

Victoria J. Madigan, Julianne A. Yuziuk, Anna M. Chiarella, +6

PLoS Pathogens

Viral ReplicationAav Vector GenomesImmunologyMolecular BiologyFinger Protein 121 +14

Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer

Timothy J. Smith, Zachary C. Elmore, Robert Fusco, +5

Molecular Therapy

EngineeringImmunologyImmunologic MechanismImmunotherapySystemic Dosing +25

Identification of New Players in Cell Division, DNA Damage Response, and Morphogenesis Through Construction of <i>Schizosaccharomyces pombe</i> Deletion Strains

Jun‐Song Chen, Janel R. Beckley, Nathan A. McDonald, +14

G3 Genes Genomes Genetics

Fungal Cell BiologyNew PlayersGeneticsMolecular GeneticsCell Cycle +18

The Golgi Calcium ATPase Pump Plays an Essential Role in Adeno-associated Virus Trafficking and Transduction

Victoria J. Madigan, Garrett E. Berry, Tyne O. Tyson, +6

Journal of Virology

Capsid-mediated control of adeno-associated viral transcription determines host range

E. Loeb, Patrick L. Havlik, Zachary C. Elmore, +7

Cell Reports

Viral ReplicationViral Polymerase MechanismGeneticsImmunologyTranscriptional Regulation +16

The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole

Zachary C. Elmore, Rodrigo X. Guillen, Kathleen L. Gould

Molecular Biology of the Cell

Spindle PoleLocalization CueMolecular RegulationMolecular BiologyCytoskeleton +20

Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration

Arvind Konkimalla, Satoshi Konishi, Yoshihiko Kobayashi, +12

iScience