Epigenetic remodeling during arsenical-induced malignant transformation

Taylor J. Jensen, Petr Novák, K.E. Eblin, +2

Carcinogenesis

Histone ModificationsChromatinDrinking WaterHistone Acetylation StateChromatin Remodeling +12

Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity

Xiao-Jun Wang, Zheng Sun, Weimin Chen, +3

Toxicology and Applied Pharmacology

Urological ResearchUrologyRenal InflammationToxicologyMonomethylarsonous Acid Toxicity +4

Monomethylarsonous acid induces transformation of human bladder cells

Tiffany Bredfeldt, Bhumasamudram Jagadish, K.E. Eblin, +2

Toxicology and Applied Pharmacology

Cell PhysiologyUrological ResearchUrologyHuman Bladder CellsCell Culture +4

Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture

K.E. Eblin, Martina E. Bowen, Douglas W. Cromey, +4

Toxicology and Applied Pharmacology

Reductive StressBiochemistryCell CultureReactive Oxygen SpecieMetabolism +5

Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation

Taylor J. Jensen, Ryan J. Wozniak, K.E. Eblin, +3

Toxicology and Applied Pharmacology

Transcriptional ActivationTranscriptional RegulationWnt5a ParticipatesArsenical-associated Malignant TransformationGenetics +7

Mitogenic Signal Transduction Caused by Monomethylarsonous Acid in Human Bladder Cells: Role in Arsenic-Induced Carcinogenesis

K.E. Eblin, Tiffany Bredfeldt, S.E. Buffington, +1

Toxicological Sciences

The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: Acute studies

K.E. Eblin, Andrew M. Hau, Thomas Jensen, +2

Toxicology

Signal TransductionHuman Bladder CellsBiochemistryMedicinePhysiology +5

Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling

K.E. Eblin, Taylor J. Jensen, Shawn M. Wnek, +3

Toxicology

Reductive StressUrotsa CellsSignal TransductionMonomethylarsonous AcidBiochemistry +10

Persistence of DNA damage following exposure of human bladder cells to chronic monomethylarsonous acid

Shawn M. Wnek, Matthew Medeiros, K.E. Eblin, +1

Toxicology and Applied Pharmacology

Monomethylarsonous AcidDna DamageHuman Bladder CellsMedicineMolecular Biology +6