Paul K. Brindle

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Martin Peifer, Lynnette Fernandez‐Cuesta, Martin L. Sos et al. · Nature Genetics · 2012 · 1.4K citations · Full text

Engineering, Somatic Variant, Tumor Heterogeneity +10

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

Seung‐Hoi Koo, Lawrence Flechner, Ling Qi et al. · Nature · 2005 · 968 citations

Energy Metabolism, Glucose Metabolism, Biochemistry +10

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

Laura Pasqualucci, David Dominguez-Sola, Annalisa Chiarenza et al. · Nature · 2011 · 919 citations · Full text

B-cell Lymphoma, Lymphoid Neoplasia, Pathology +4

Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

Qihuang Jin, Li‐Rong Yu, Lifeng Wang et al. · The EMBO Journal · 2010 · 868 citations · Full text

Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation

Christopher G. Vecsey, Joshua D. Hawk, K. Matthew Lattal et al. · Journal of Neuroscience · 2007 · 830 citations · Full text

Chromatin, Synaptic Plasticity, Hdac Inhibitors +15