The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

Qizhao Huang, Xia Wu, Zhiming Wang, +25

Cell

Bona Fide RespondersPd-1/pd-l1 BlockadeCancer ImmunosurveillanceT-regulatory CellImmunology +6

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

Xiangyu Chen, Li Ren, Zhiwei Pan, +21

Cellular and Molecular Immunology

Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19

Xiangyu Chen, Zhiwei Pan, Shuai Yue, +19

Signal Transduction and Targeted Therapy

Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa

Yao Wang, Leiqiong Gao, Xiancai Rao, +11

Scientific Reports

An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy

Xiangyu Chen, Shuai Yue, Ziyu Li, +27

Nature Cancer

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

Xiangyu Chen, Li Ren, Zhiwei Pan, +21

ImmunologyViral PathogenesisMemory B CellsViral Structural ProteinHuman Monoclonal Antibodies +14

The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

Leiqiong Gao, Jing Zhou, Sen Yang, +13

Signal Transduction and Targeted Therapy

Nasal Spray of Neutralizing Monoclonal Antibody 35B5 Confers Potential Prophylaxis Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Small-Scale Clinical Trial

Yao Lin, Shuai Yue, Yang Yang, +19

Clinical Infectious Diseases

Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19

Xiangyu Chen, Zhiwei Pan, Shuai Yue, +19

VaccinationDisease SeverityHumoral ResponseImmunologyCovid-19 Pandemic +6

High-mobility group box-1 protein from CC10⁺ club cells promotes type 2 response in the later stage of respiratory syncytial virus infection

Sisi Chen, Guangyuan Yu, Jun Xie, +8

American Journal of Physiology-Lung Cellular and Molecular Physiology