Thea Bismo Strøm

PCSK9 acts as a chaperone for the LDL receptor in the endoplasmic reticulum

Thea Bismo Strøm, Kristian Tveten, Trond P. Leren · Biochemical Journal · 2013 · 46 citations

Life Sciences, Biochemistry, Molecular Biology +16

Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum

Thea Bismo Strøm, Kristian Tveten, Jon K. Laerdahl et al. · FEBS Open Bio · 2014 · 41 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor–independent pathways

Jamie Cameron, Martin P. Bogsrud, Kristian Tveten et al. · Translational research · 2012 · 36 citations

Life Sciences, Biochemistry, Pharmacokinetics +9

Disrupted recycling of the low density lipoprotein receptor by PCSK9 is not mediated by residues of the cytoplasmic domain

Thea Bismo Strøm, Øystein L. Holla, Kristian Tveten et al. · Molecular Genetics and Metabolism · 2010 · 35 citations

Life Sciences, Biochemistry, Molecular Biology +14

Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR

Thea Bismo Strøm, Jon K. Laerdahl, Trond P. Leren · Human Molecular Genetics · 2015 · 33 citations · Full text

Life Sciences, Genetics, Molecular Biology +17