Takashi Shimayama

Generality of the NUX Rule: Kinetic Analysis of the Results of Systematic Mutations in the Trinucleotide at the Cleavage Site of Hammerhead Ribozymes

Takashi Shimayama, Satoshi Nishikawa, Kazunari Taira · Biochemistry · 1995 · 161 citations

Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages

Takashi Shimayama, Fumiko Nishikawa, Satoshi Nishikawa et al. · Nucleic Acids Research · 1993 · 127 citations · Full text

Viral Replication, Hammerhead Ribozymes, Biochemistry +13

Theoretical and Experimental Considerations on the Hammerhead Ribozyme Reactions: Divalent Magnesium Ion Mediated Cleavage of Phosphorus-Oxygen Bonds

Masami Uebayasi, Tadafumi Uchimaru, Shinya Y. Sawata et al. · The Journal of Organic Chemistry · 1994 · 49 citations

Phosphorus-oxygen Bonds, Molecular Sciences, Bioorganic Chemistry +13

High-resolution NMR study of a synthetic oligoribonucleotide with a tetranucleotide GAGA loop that is a substrate for the cytotoxic protein, ricin

Masaya Orita, Fumiko Nishikawa, Takashi Shimayama et al. · Nucleic Acids Research · 1993 · 48 citations · Full text

Nmr Spectroscopy, Depurination Site, Biomolecular Structure Prediction +16

Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions

S. Y. Sawata, Takashi Shimayama, Makoto Komiyama et al. · Nucleic Acids Research · 1993 · 47 citations · Full text

Dna Nanotechnology, Dna-armed Hammerhead Ribozymes, Cleavage Rates +15