T.L. McDonald

CYP2E1 is not involved in early alcohol-induced liver injury

Hiroshi Kono, Blair U. Bradford, Ming Yin et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1999 · 164 citations

Pathology, Fatty Liver Disease, Reactive Oxygen Species +17

Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α 1 1Abbreviations: EGb 761, Ginkgo biloba extract; LPS, lipopolysaccharide; ROIs, reactive oxygen intermediates; TNF, tumor necrosis factor; IL, interleukin; COX, cyclooxygenase; iNOS, inducible nitric oxide synthase; TLR, Toll-like receptor; LBP, lipid binding protein; NF-κB, nuclear factor-κB; IKK, IκB kinase; AP-1, activator protein 1; ATF, activating transcription factor; CRE, cyclic AMP response element; CREB, cyclic AMP binding protein; C/EBP, CCAAT/enhancer binding protein; ARE, AU-rich element; -UTR, untranslated region; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-related kinase; MEKK, MAPK/ERK kinase kinase; MEK, MAPK/ERK kinase; JNK/SAPK, Jun N terminal kinase/stress-activated protein kinase; EMSA, electrophoretic mobility shift assay; DTT, dithiothreitol; PMSF, phenylmethylsulfonyl fluoride; and ECL, enhanced chemiluminescence.

Teri L. Wadsworth, T.L. McDonald, Dennis R. Koop · Biochemical Pharmacology · 2001 · 145 citations

Relationship between fatigue, sleep quality and inflammatory cytokines during external beam radiation therapy for prostate cancer: A prospective study

Emma B. Holliday, Nathan F. Dieckmann, T.L. McDonald et al. · Radiotherapy and Oncology · 2015 · 47 citations · Full text

Inflammatory Cytokines, Radiation Medicine, Radiation Therapy +6

Localized External Beam Radiation Therapy (EBRT) to the Pelvis Induces Systemic IL-1Beta and TNF-Alpha Production: Role of the TNF-Alpha Signaling in EBRT-Induced Fatigue

T.L. McDonald, Arthur Hung, Charles R. Thomas et al. · Radiation Research · 2015 · 13 citations

Prostate Cancer Patients, Immunology, Immune Regulation +24